Age-Related Decline in Strength as Decline Neurons

“What we have here is (a) failure to communicate,” said the Captain in the 1967 film Cool Hand Luke. This line rings true today as it relates to the failure of physiologists to communicate the mechanisms of muscle strength to the geriatrics community, where the lack of muscle strength observed in older adults holds high clinical significance. Similarly, there is a relative under recognition in the scientific community for the potential role of the brain’s failure to communicate with ske...

 A Succinct Definition of Lactate

Lactate is a dynamic substrate with great potential as an energy source in sports drinks. To date, however, the efficacy of adding lactate to these drinks has been sparsely assessed [5,15,16]. Lactate was once considered a metabolic waste but is now recognized as an important energy substrate in the body. Lactate is the main product of carbohydrate metabolism and can be used as a fuel in working muscle cells shuttled to other tissues such as the heart where lactate is fuel [17], or to the liv...

 The Effects of Aging and How Exercise Counteracts Them

• Motor neurons die, particularly from age 60 onward. This causes connections between muscle fibers to wither — and that, in turn, eventually leads to loss and shrinking of muscle fibers. As a result, muscles get smaller and a person gets weaker, says Sandra Hunter, an associate professor of exercise science at Marquette University in Milwaukee. "Physical activity can offset some of that," she says. "But there is this biological aging process going on — the neurons will die regardle...