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As Lao-tzu put it two thousand years ago: Man at his birth is supple and tender, but in death he is rigid and hard. Plants when young are sinuous and moist, but when old are brittle and dry. Thus suppleness and tenderness are signs of life, While rigidity and hardness are signs of death.
If 234 000 deaths from COVID-19 could have been prevented with a primary series of vaccinations (https://bit.ly/3XrFXfz) between June 2021 and March 2022, I estimate that 140 400 of these deaths would have been among Republicans. This is, of course, not a surprise because Republicans are less likely to be vaccinated…
Although metabolism does tend to shift with age, decades of research demonstrate that such changes are not set in stone. By regularly checking the key biomarkers that reveal your muscle mass, mitochondrial health, thyroid function, inflammatory status, and glucose regulation, you can detect subtle signs of slowdown…
Previously in DO-HEALTH (including all 2,157 participants), we reported that omega-3 alone reduced the rate of infections by 13% (ref. 22) and the rate of falls by 10% (ref. 23), and all three interventions combined showed a significant additive benefit on reducing prefrailty by 39% (ref. 24) and incident invasive…
Every age has its signature afflictions. Thus, a bacterial age existed; at the latest, it ended with the discovery of antibiotics. Despite widespread fear of an influenza epidemic, we are not living in a viral age. Thanks to immunological technology, we have already left it behind. From a pathological standpoint, the…
The reason for that is because exercise causes stress and that stress turns on a whole raft of beneficial effects. And there are really two kinds of this stress. Now, the first kind is energetic stress. Like I went for a run this morning, I spent probably about 500 calories running and I can only do so many things…
Now, the other kind of stress Structural stress from activity that physical activity cause is structural stress. Now, when I was running this morning, for example, my mitochondria were generating all kinds of ATP to fuel my body, but my mitochondria were also spewing out all kinds of reactive oxygen species, which…
In young rats, the researchers found low levels of the protein-breaking enzyme trypsin, although the tiny folds (villi) of the small intestine and the lungs contained more of this molecule. However, trypsin levels were much higher in old animals. “High densities are on sections of the intestine, liver, and lung…
One way of gauging the current diversity of cultures is to consider the range of responses countries made to the COVID-19 pandemic.120 There was, of course, some diversity, from the ultrastrict lockdowns in China to the more moderate response in Sweden. But the range of responses was far more limited than it could…
The best that we have seen so far is a poor guide to what is possible. To get some inkling of this, consider the life of a rich man in Britain in 1700—a man with access to the best food, health care, and luxuries available at the time. For all his advantages, such a man could easily die of smallpox, syphilis, or…
"The muscles we use to breathe atrophy, just like the rest of our muscles tend to do as we get older," explains researcher Daniel Craighead, an integrative physiologist at the University of Colorado Boulder. To test what happens when these muscles are given a good workout, he and his colleagues recruited healthy…
I HAVE THIS recurring nightmare. Jonas Salk has just announced his cure for polio. A bill is introduced in Congress to require mandatory inoculation of school children under HEW direction. Opposition then appears. Ronald Reagan urges "free choice by parents rather than compulsion by government." Mobil runs…
Panchin knows the idea of cancer-derived animals sounds far-fetched — so much so that, in the paper, he and his co-authors refer to them as Scandals (an acronym for “speciated by cancer development animals”). [...] According to Panchin’s three-step scenario, a Scandal would start off as a cancer, but not just any…
There’s a continuing struggle between complexity and robustness in both evolution and human design. A kind of survival imperative, whether in biology, engineering, or business requires that simple, fragile systems become more robust. But the mechanisms to increase robustness will in turn make the system considerably…
If the translation of Do predicates the meaning of one's Truth, what we call home for the purpose of such training is Dojo. Jo (translated as the place, or the Hall) is the center of total focus, where all venerable learning is to take place through myriads of human struggles and energetic interactions. It is…
De Koven’s concept of play is predicated on the idea that play, as a purposeless act, is the means through which we can build community and move closer to living better lives. He ultimately moves away from the idea of playing games and towards a purer idea of play beyond games, play as mastery over nothing in…
Hartmann, in his work on the Anthropoid Apes (289, p. 301), quotes, approvingly, the words of Vogt: ‘When we consider the principles of the modern theory of evolution, as it is applied to the history of development, we are met by the important fact that in every respect the young ape stands nearer to the human child…
The Real Significance of Play.—This scheme is, doubtless, imperfect, as critics of Groos’s book have taken occasion to point out, but the idea which underlies it all is a most suggestive and illuminating one, when rightly understood. In his latest work on the play of man, which has recently appeared, Groos makes clear…
hough it’s not easy to pinpoint the causes of the rise in IQ scores, it’s no paradox that a heritable trait can be boosted by changes in the environment. That’s what happened with height, a trait that also is highly heritable and has increased over the decades, and for some of the same reasons: better nutrition and…
When I was a boy, a popular literary genre for children was the heroic biography of a medical pioneer such as Edward Jenner, Louis Pasteur, Joseph Lister, Frederick Banting, Charles Best, William Osler, or Alexander Fleming. On April 12, 1955, a team of scientists announced that Jonas Salk’s vaccine against polio—the…