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Multivariate analysis suggested that antipyretic therapy prolonged illness in subjects infected with influenza A, but its use was the result of prolonged illness in those infected with S. sonnei. The precise nature of these relationships requires a prospective, randomized, placebo-controlled trial.
Warm-blooded animals have an elaborate physiological control system to maintain a constant body temperature. In man, this temperature is about 37°C. Any significant deviation from this temperature puts stress on the body and makes it difficult to maintain metabolic processes at their normal rates. Why then, during…
To put our lower bound for fp into perspective, consider that approximately 41 400 (95% CI: 27 100–55 700) deaths per year are attributed to seasonal influenza epidemics in the United States [43] (and an order of magnitude more worldwide [44]). Taken at face value, our results indicate, for example, that if Embedded…
In 1986, John Holloszy of Washington University immersed his lab rats in shallow, cool water for four hours each day. They burned so many extra calories that they ate half again as much as control rats, but weighed less. The cold rats lived 10% longer, on average. Holloszy framed his report on this experiment not as a…
On a standard piano keyboard, one octave is divided into 7 whole tones: A, B, C, D, E, F and G. In between these tones are 5 further notes which can be called either sharps or flats: A# (Bb), C# (Db), D# (Eb), F# (Gb), G# (Ab). (whether it's a sharp of a flat doesn't really matter, the note has the same frequency…
The most merciful thing in the world, I think, is the inability of the human mind to correlate all its contents. We live on a placid island of ignorance in the midst of black seas of infinity, and it was not meant that we should voyage far. The sciences, each straining in its own direction, have hitherto harmed us…
Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables. It has been previously proposed that non-linear properties of dendrites enable neurons to recognize multiple patterns. In this…
The study of domesticated animals since Darwin’s influential work (1868) has culminated in the formation of a set of changes that are claimed to distinguish domestic populations from wild species (for recent outlines of these see Price 1984, 1999; Hemmer 1990; Tchernov and Horwitz 1991; Hall 1993; Teichert 1993; Smith…
Before we discuss what current research tells us about memory and recall, it may be helpful to address a common misconception that emerged from the work ofCanadian neurosurgeon Wilder Penfield in the 1930s and 1940s. Penfield reported that during surgery, an electrical stimulation of the temporal lobe produced…
This reversibility and this polyvalency endow analogy with a universal field of application. Through it, all the figures in the whole universe can be drawn together. There does exist, however, in this space, furrowed in every direction, one particularly privileged point: it is saturated with analogies (all analogies…
In absolute numbers, of course, civilized societies are matchless in the destruction they have wreaked. But should we look at absolute numbers, or at relative numbers, calculated as a proportion of the populations? The choice confronts us with the moral imponderable of whether it is worse for 50 percent of a…
It is one thing if a child’s IQ is elevated over time because she is drilled daily on vocabulary and basic number facts (two of the subtests of major IQ batteries). But Flynn and others have shown that these are not the areas where IQ has risen much. It is in what Flynn refers to as “on-the-spot reasoning” about…
There is nothing really the matter with the concept of g; it is just that we have misused it by making it the omnipresent concept in our study of cognitive abilities. Intelligence is important on three levels, namely, brain physiology, individual differences, and social trends (collectively, BIDS). The core of a BIDS…
The most potent facet of our environment is other people. When something, perhaps the popularity basketball got from television, triggered greater participation in basketball, the average performance rose as individuals played more and got better. Initially, a few people learn to shoot with either hand, then others…
The irony is that knowing that the G.I. Joe Fallacy is a fallacy is—as the fallacy would predict—less than half the battle. As is knowing that people tend to experience $19.99 as a significantly lower price than $20.00. Even if you know about this left-digit anchoring effect, the first item will still feel like a…
Life becomes different, and it carries on. Since the majority of invasive species are relatively benign, they add to an island’s overall biodiversity. The ecologist Dov Sax at Brown University in Rhode Island points out that non-native plants have doubled the botanical biodiversity of New Zealand – there are 2,104…
Most of us do not believe a religion – Christianity, Islam, Pastafarianiasm – requires literal belief in order to provide spiritual enlightenment. That is, we can be part of a community without becoming indoctrinated. There are many levels of belief. By design, the only dogma allowed in the Church of the Flying…
My vision of life is that everything extends from replicators, which are in practice DNA molecules on this planet. The replicators reach out into the world to influence their own probability of being passed on. Mostly they don't reach further than the individual body in which they sit, but that's a matter of practice…
They found that, unsurprisingly, the people who did not exercise at all were at the highest risk of early death. But those who exercised a little, not meeting the recommendations but doing something, lowered their risk of premature death by 20 percent. Those who met the guidelines precisely, completing 150 minutes per…
It is clear that if the phonic substance lost its privilege, it was not to the advantage of the graphic substance, which lends itself to the same substitutions. To the extent that it liberates and is irrefutable, glossematics still operates with a popular concept of writing. However original and irreducible it might…