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Anomaly (2) was observed by Fred Griffith, decades before DNA and the genetic code. He found that if you inject a heat-treated, dead, virulent species of bacteria (pneumococcus S) into a rat previously infected with a nonvirulent species (pneumococcus R), then species R became transformed into species S, thereby…
let’s revisit that initial encounter in The Sign of Four, when Mary Morstan, the mysterious lady caller, first makes her appearance. Do the two men see Mary in the same light? Not at all. The first thing Watson notices is the lady’s appearance. She is, he remarks, a rather attractive woman. Irrelevant, counters…
Holmes and Watson don’t just differ in the stuff of their attics—in one attic, the furniture acquired by a detective and selfproclaimed loner, who loves music and opera, pipe smoking and indoor target practice, esoteric works on chemistry and renaissance architecture; in the other, that of a war surgeon and…
The way Watson plays the game also requires massive amounts of pattern matching. The supercomputer has been loaded with hundreds of millions of unconnected digital documents, including encyclopedias and other reference works, newspaper stories, and the Bible. When it receives a question, it immediately goes to work to…
All of these people, should they desire, can indicate events and details they remember differently. But there is one unfortunate exception. In 1958, Rosalind Franklin died at the early age of thirty-seven. Since my initial impressions of her, both scientific and personal (as recorded in the early pages of this book)…
Rosy's instant acceptance of our model at first amazed me. I had feared that her sharp, stubborn mind, caught in her self-made antihelical trap, might dig up irrelevant results that would foster uncertainty about the correctness of the double helix. Nonetheless, like almost everyone else, she saw the appeal of the…
I was preoccupied with sex, but not of a type that needed encouragement. The mating habits of bacteria were admittedly a unique conversation pieceçabsolutely no one in his and Odile's social circle would guess bacteria had sex lives. On the other hand, working out how they did it was best left to minor minds. Rumors…
BY mid-November, when Rosy's talk on DNA rolled about, I had learned enough crystallographic argument to follow much of her lecture.. Most important, I knew what to focus attention upon. Six weeks of listening to Francis had made me realize that the crux of the matter was whether Rosy's new X-ray pictures would lend…
By the time I was back to Copenhagen, the journal containing Linus' article had arrived from the States. I quickly read it and immediately reread it. Most of the language was above me, and so I could only get a general impression of his argument. I had no way of judging whether it made sense. The only thing I was sure…
Pauling's talk was made with his usual dramatic flair. The words came out as if he had been in show business all his life. A curtain kept his model hidden until near the end of his lecture, when he proudly unveiled his latest creation. Then, with his eyes twinkling, Linus explained the specific characteristics that…
Even worse, Maurice continually frustrated Francis by never seeming enthusiastic enough about DNA. He appeared to enjoy slowly understating important arguments. It was not a question of intelligence or common sense Maurice clearly had both; witness his seizing DNA before almost everyone else. It was that Francis felt…