NgR1 Improves Brain Plasticity in Adult Mice

Experience rearranges anatomical connectivity in the brain, but such plasticity is suppressed in adulthood. We examined the turnover of dendritic spines and axonal varicosities in the somatosensory cortex of mice lacking Nogo Receptor 1 (NgR1). Through adolescence, the anatomy and plasticity of ngr1 null mice are indistinguishable from control, but suppression of turnover after age 26 days fails to occur in ngr1?/? mice. Adolescent anatomical plasticity can be restored to 1-year-old mice by c...

 Schools Kill a Child's Curiosity

All children are curious and I wonder by what process this trait becomes developed in some and suppressed in others. I suspect again that schools and colleges help in the suppression insofar as they meet curiosity by giving the answers, rather than by some method that leads from narrower questions to broader questions. It is hard to satisfy the curiosity of a child, and even harder to satisfy the curiosity of a scientist, and methods that meet curiosity with satisfaction are thus not apt to f...

 Hormones on the Brain

At school, boys are fidgety, difficult, inattentive, and slow to learn, compared to girls. Nineteen out of every twenty hyperactive children are boys. Four times as many boys as girls are dyslexic and learning disabled. "Education is almost a conspiracy against the aptitudes and inclinations of a schoolboy," wrote psychologist Dianne McGuiness, a sentiment to which almost every man with a memory of school will raise a hearty cry of assent. But another fact begins to emerge at school. Girls a...