The Artilect Perspective of a Human Intelligence

It is not exaggerating to say that there is quite a close analogy between an artilect trying to communicate with a human being, and a human being trying to communicate with a rock. To make another analogy, consider your feelings towards a mosquito as it lands on the skin of your forearm. When you swat it, do you stop to consider that the creature you just killed is a miracle of nano-technological engineering, that scientists of the 20th century had absolutely no way of building. The mosquito...

 Stones are Chaos

The difference between a piece of stone and an atom is that an atom is highly organised, whereas the stone is not. The atom is a pattern, and the molecule is a pattern, and the crystal is a pattem; but the stone, although it is made up of these pattems, is just a mere confusion. It's only when life appears that you begin to get organisation on a larger scale. Life takes the atoms and molecules and crystals; but, instead of making a mess of them like the stone, it combines them into new and mo...

 The Signaling Pathway

In a typical signaling pathway, proteins are continually being modified and demodified. Kinases and phosphatases work ceaselessly like ants in a nest, adding phosphate groups to proteins and removing them again. It seems a pointless exercise, especially when you consider that each cycle of addition and removal costs the cell one molecule of ATP—one unit of precious energy. Indeed, cyclic reactions of this kind were initially labeled “futile.” But the adjective is misleading. The additio...

 Vitamins Come from Living Things

Every vitamin is made by living cells — either our own, or in other species. Vitamin D is produced in our skin, for example, when sunlight strikes a precursor of cholesterol. A lemon tree makes vitamin C out of glucose. Making a vitamin is often an enormously baroque process. In some species, it takes 22 different proteins to craft a vitamin B12 molecule. While a protein may be made up of thousands of atoms, a vitamin may be made up of just a few dozen. And yet, despite their small size, v...

 We are Machines that Carry Genes

We are survival machines, but 'we' does not mean just people. It embraces all animals, plants, bacteria, and viruses. The total number of survival machines on earth is very difficult to count and even the total number of species is unknown. Taking just insects alone, the number of living species has been estimated at around three million, and the number of individual insects may be a million million million. Different sorts of survival machine appear very varied on the outside and in their i...

 Chemistry Logic is a Triumph of the Human Mind

The ingenuity and effective logic that enabled chemists to determine complex molecular structures from the number of isomers, the reactivity of the molecule and of its fragments, the freezing point, the empirical formula, the molecular weight, etc., is one of the outstanding triumphs of the human mind.

 The Advancement of Science Out of the Amateur

To-day, science has withdrawn into realms that are hardly understanded of the people. Biology means very largely histology, the study of the cell by difficult and elaborate microscopical processes. Chemistry has passed from the mixing of simple substances with ascertained reactions, to an experimentation of these processes under varying conditions of temperature, pressure, and electrification—all requiring complicated apparatus and the most delicate measurement and manipulation. Similarly, ...

 Watson Admits to Misunderstanding Rosalind Franklin

Rosy's instant acceptance of our model at first amazed me. I had feared that her sharp, stubborn mind, caught in her self-made antihelical trap, might dig up irrelevant results that would foster uncertainty about the correctness of the double helix. Nonetheless, like almost everyone else, she saw the appeal of the base pairs and accepted the fact that the structure was too pretty not to be true. Moreover, even before she learned of our proposal, the X-ray evidence had been forcing her more th...

 How the Adverse Affects of Stress Were Discovered

Lots of research has gone into trying to understand how maternal stress affects brain development. And we have begun to answer this question at the most intimate level possible: the level of cell and molecule. For this progress we mostly can thank the klutzy researcher Hans Selye. He is the founder of the modern concept of stress. As a young scientist, Selye would grind up “endocrine extracts”, which presumably contained active stress hormones, and inject them into rats to see what the ra...