Health Concerns Spark Adult Interest in Science
Beginning in middle age and continuing through later adulthood, individuals are often motivated by events in their own lives or the lives of significant others to obtain health-related information.^^ Health-related concerns draw many adults into a new domain of science learning. At the same time, with retirement, older adults have more time to devote to personal interests. Their science learnmg addresses long-standing scientific interests as well as new areas of interest.^^
Adults differ fr...
notesAs do novelty, wonder, self interest, and relevance to personal.
Cardiorespiratory Fitness (CRF) Lowers Cancer Risk
A well-established, graded, inverse association exists between cardiorespiratory fitness (CRF) and risk of cardiovascular disease (CVD) as well as all-cause mortality in numerous healthy and clinical adult populations.1- 3 Compared with those classified in the lowest CRF category (<7.9 metabolic equivalents [METs]), individuals in the highest CRF category (≥10.9 METs) have a 1.6- to 1.7-fold lower risk of CVD and all-cause mortality, respectively.4 Accordingly, measurement of CRF via for...
1 From Time Magazine article on the study:
Here’s the best part: it doesn’t take a lot of exercise to have a big health impact, Lakoski found. “Just a small improvement in fitness made a difference in survival of those that developed cancer,” she says. Compared to men who could run 12-minute miles on the treadmill at age 50, men who ran slightly faster 11.5-minute miles had an additional 10% decrease in cancer death and an extra 25% decrease in cardiovascular death among those who developed cancer in the study.
Predictability and the Base Rate
Whenever a statistician wants to predict the likelihood of some event based on the available evidence, there are two main sources of information that have to be taken into account: (1) the evidence itself, for which a reliability figure has to be calculated; and (2) the likelihood of the event calculated purely in terms of relative incidence. The second figure here is the base rate. Since it is just a number, obtained by the seemingly dull process of counting, it frequently gets overlooked wh... notesKeith Devlin explains why the accuracy of tests and measurments must take into account the base rate for the phenomenon.
The Fundamentals of Cancer
Cancer, we now know, is a disease caused by the uncontrolled growth of a single cell. This growth is unleashed by mutations—changes in DNA that specifically affect genes that incite unlimited cell growth. In a normal cell, powerful genetic circuits regulate cell division and cell death. In a cancer cell, these circuits have been broken, unleashing a cell that cannot stop growing.
That this seemingly simple mechanism—cell growth without barriers—can lie at the heart of this grotesque an... notesIt is a mutated cell, a renegade, the key is to keep it from mutating.
People Who Take Supplements are Less Healthy
Antioxidation vs. oxidation has been billed as a contest between good and evil. The battle takes place in cellular organelles called mitochondria, where the body converts food to energy, a process that requires oxygen and so is called oxidation. One consequence of oxidation is the generation of electron scavengers called free radicals (evil). Free radicals can damage DNA, cell membranes, and the lining of arteries; not surprisingly, they've been linked to aging, cancer, and heart disease. To ... notesPeople who eat lots of fruits and vegetables have lower incidence of cancer and other diseases, but people who take nutritional supplements meant containing high doses of the nutrients found in fruits in vegetables die at much higher rates.
The Skeptic's Horoscope
For Capricorn, Aquarius, Pisces, Aries, Taurus, Gemini, Cancer, Leo, Virgo, Libra, Scorpio, and Sagittarius:
"The coming year is likely to present challenges; these trials are when your true character will show. Trusted friends can provide assistance in particularly pressing situations. Make use of the skills you have to compensate for ones you lack. Your reputation in the future depends on your honesty and integrity this year. Monetary investments will prove risky; inform yourself as much a... notesExcellent illustration of how nebulous statements can apply to anyone.
An Optimistic View of the Rise of Cancer
The fact that death from cancer is on the increase is not only a problem of medicine, but its at the same time testifies to the wonderful efficiency of medical science... [as it] enables more persons top live long enough to develop some kind of cancer in old and less resistant tissues. It means people are living long enough to get cancer.
A Clock Stopped at the Moment Feynman's Wife Died
Sometimes we can actually pin down the explanation of a weird coincidence. A great American scientist called Richard Feynman tragically lost his wife to cancer, and the clock in her room stopped at precisely the moment she died. Goose-pimples! But Dr Feynman was not a great scientist for nothing. He worked out the true explanation. The clock was faulty. If you picked it up and tilted it, it tended to stop. When Mrs Feynman died, the nurse needed to record tl the time for the official death ce... notesBut he traced the phenomenon to a faulty mechanism in the clock that triggered when the nurse picked it up to record the time of death.
Phytochemical Exposure Prevents Cancer in Mice
Williams’s experiments have shown that the offspring of mice who ingest a phytochemical derived from cruciferous vegetables like broccoli, cabbage, and brussels sprouts during pregnancy were much less likely to get cancer, even when exposed to a known carcinogen. The same is true of the offspring of mice who were given green tea during pregnancy. After they were weaned, the offspring in William’s experiments never encountered these protective chemicals again, yet their exposure during pre... notesEven when exposed to known carcinogens.
Cancer is an Early Form of Life on Earth
The genes of cellular cooperation that evolved with multicellularity about a billion years ago are the same genes that malfunction to cause cancer. We hypothesize that cancer is an atavistic condition that occurs when genetic or epigenetic malfunction unlocks an ancient 'toolkit' of pre-existing adaptations, re-establishing the dominance of an earlier layer of genes that controlled loose-knit colonies of only partially differentiated cells, similar to tumors. The existence of such a toolkit i...It grows similar to early multicellular life and may be the result of later genes in our bodies which are meant to suppress it malfunctioning.
