08 MAR 2016 by ideonexus

 Physical and Actuarial Escape Velocities

The escape velocity cusp is closer than you might guess. Since we are already so long lived, even a 30% increase in healthy life span will give the first beneficiaries of rejuvenation therapies another 20 years—an eternity in science—to benefit from second-generation therapies that would give another 30%, and so on ad infinitum. Thus, if first-generation rejuvenation therapies were universally available and this progress in developing rejuvenation therapy could be indefinitely maintained,...
Folksonomies: longevity life-extension
Folksonomies: longevity life-extension
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06 MAR 2015 by ideonexus

 Paradigm Shift: Everyone Will have a Timeline

In 10 years, every human connected to the Internet will have a timeline. It will contain everything we’ve done since we started recording, and it will be the primary tool with which we administer our lives. This will fundamentally change how we live, love, work, and play. And we’ll look back at the time before our feed started — before Year Zero — as a huge, unknowable black hole. This timeline — beginning for newborns at Year Zero — will be so intrinsic to life that it will quic...
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The ubiquitous tracking of so much data on everyone means we are entering a new age.

04 MAR 2015 by ideonexus

 An Algorithm for Predicting Longevity

For the test, participants exercised on a treadmill at increasing speed and incline. While they were exercising, the researches measured peak heart rate (%MPHR) and their ability to withstand physical exertion. On that latter point, they measured metabolic equivalents, or METs, which gauges how much energy the body expends during exercise. The more intense the exercise, the higher the METs (e.g. slow walking = ~2 METs, whereas running = ~8 METs). [...] FIT Treadmill Score = %MPHR 12(M...
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You can get your MPHR for your age here. I found a chart of METS here for various exercises.

Activity METS Activity METS
Aerobic Dancing 6.0 Running 12 min/mile 8.5
Backpacking 7.0 Racquetball 8.0
Badminton 7.0 Rugby 8.3
Basketball 6.0 Skating ice/roller 7.0
Bicycling - 24mph 5.0 Skiing cross country 8.0
Calisthenics 4.5 Soccer 8.0
Golf 5.0 Softball 5.0
Gymnastics 5.5 Swimming 6.0
Handball 8.0 Tennis 7.0
Hockey 8.0 Volleyball 4.0
Horse riding 3.5 Walking 3.5
Running 8 min/mile 12.5 Weight lifting 4.5

Bruce Protocol

Stage Minutes % grade km/h MPH METS
1 3 10 2.7 1.7 5
2 3 12 4.0 2.5 7
3 3 14 5.4 3.4 10
4 3 16 6.7 4.2 13
5 3 18 8.0 5.0 15
6 3 20 8.8 5.5 18
7 3 22 9.6 6.0 20

Total Durations = 21 minutes

So, if I'm understanding this correctly. If I reach a 160 heart rate out of 179.0 MPHR predicted for my 41 years of age while running 12 minute miles worth 8.5 METS. My score would be:

83.7 12(8.5) - 4(41) = 21.7

The same heart rate for my age running 8 minute miles:

83.7 12(8.5) - 4(41) = 69.7

22 NOV 2013 by ideonexus

 Game That Adds 7.5 Minutes to Your Life

Now, I could tell you what these four types of strength are, but I'd rather you experience them firsthand. I'd rather we all start building them up together right now. So here's what we're going to do. We're going to play a quick game together. This is where you earn those seven and a half minutes of bonus life that I promised you earlier. All you have to do is successfully complete the first four SuperBetter quests. And I feel like you can do it. I have confidence in you. So, everybody read...
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Quick game that hits on four aspects of a healthy life. The speaker then suggests using those seven minutes on actions that will get you even more longevity.

21 MAY 2013 by ideonexus

 Different Cells are Replaced at Different Rates

Different types of cells have different lifespans, e.g.:  we shed our skin cells about every 35 days red blood cells live about 120 days, platelets 6 days and white cells less than a day most of the adult skeleton is replaced about every 10 years the average age of a fat cell seems to be about 10 years a 25-year-old heart replaces about 1% of all its cardiomyocytes (heart muscle cells ) over the course of a year, while a 75-year-old heart replaces about half a percent ...
Folksonomies: biology physiology
Folksonomies: biology physiology
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Neural cells are not replaced at all.

05 JUN 2012 by ideonexus

 Rapid Growth of Physics

As a result of the phenomenally rapid change and growth of physics, the men and women who did their great work one or two generations ago may be our distant predecessors in terms of the state of the field, but they are our close neighbors in terms of time and tastes. This may be an unprecedented state of affairs among professionals; one can perhaps be forgiven if one characterizes it epigrammatically with a disastrously mixed metaphor; in the sciences, we are now uniquely privileged to sit si...
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Reminds me of the rapid growth of IT, where working with people just 10 years older marks a phenomenal difference in technological understanding.

31 JUL 2011 by ideonexus

 Music Lessons Teach Children Emotional Nuance

10 years of music lessons There’s another powerful way to fine-tune a child’s hearing for the emotional aspects of speech: musical training. Researchers in the Chicago area showed that musically experienced kids—those who studied any instrument for at least 10 years, starting before age 7—responded with greased-lightning speed to subtle variations in emotion-laden cues, such as a baby’s cry. The scientists tracked changes in the timing, pitch, and timbre of the baby’s cry, all t...
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Children who begin music lessons before the age of seven have a greater ability to detect emotional nuance than children who do not.

eBooks and The Science Community

Carl Zimmer, Tom Levenson, David Dobbs, John Dupuis

Different perspectives. Author of ebook, someone writing an ebook, and librarian with books that don’t go up on shelves.

Carl Zimmer

·         wrote first book in 1998. eBooks were the future, but vanished with dot-com bust.

·         eBook graph is skyrocketing while publishing is used to slow gently declining graphs.

·         Smashwords: publish and distribute books.

·         Put together an ebook as just a book, text: OR put book together as an app.

·         David Eagleman – example of book with media

·         Marcus Chown – Solar System ebook

·         These super dynamic ebooks are not books, they aren’t linear, they are encyclopedias with articles.

Tom Levenson

·         “There’s nothing new under the sun.”

·         After Gutenberg invention there were millions of books, before there were only thousands.

·         Gutenberg Moment: explosion of data

·         Birth of book trade, birth of audience, new occupation of writers.

·         Becoming of the Books – recommended book on the growth of the book trade

·         Emergence of copyright law.

·         Half of books were religious, ten percent were law, and ten percent were science.

·         Each development in the media has unpredictable impacts on the genres and creative expression.

·         When you get cheap paper, you get newspapers and pulp novels.

·         What new genres will emerge from the ebook? ME: A hypertext document. Collection of quotes, links to authors and indexes.

·         Appbooks are a different medium. ME: But they are no different from websites.

·         Book isn’t dead. There are niche books. Cory Doctorow sells books in all different mediums.

·         We are at a Lumier Brother’s stage in app books, it’s enough to show simple tricks, but that won’t last, we need to go more substansive.

David Dobbs

·         Writing a regular book, but is also working on an app book version of it.

·         Slider to change gene varables to watch genes turn on and off.

·         Illustrations eliminate words. Books has words, which get eliminated in the app.

·         Different marketing versions of the book: basic ebook  $10, app book $15, cheaper modules $3

John Dupuis

·         Will spend $100,000 on ebooks this year, mostly computer science and engineering.

·         Authors and publishers are often suspicious of librarians because their job is to provide access to content to people who can’t afford it or won’t pay for it.

·         What is the ebook business model? It will go the same route as the music industry. People will still pay for books, but in an itunes model.

·         What’s the sharing model for apps? It works on your ipad now, but what will it work on 10 years from now. Will historians of writing be able to access the Elements a hundred years from now.

·         Apps allow monetizing every reading transaction, and that is evil.


·         Nancy Schuler: writing ipad text for National Geographic, love you graphics designers

·         ME: Google Android version of books?

·         JA Konrath: making money with DIY publishing

·         Comment: I don’t want you wasting time working on apps if it detracts from your time spent crafting good writing.