Fever-Reducer Extends Illness

Multivariate analysis suggested that antipyretic therapy prolonged illness in subjects infected with influenza A, but its use was the result of prolonged illness in those infected with S. sonnei. The precise nature of these relationships requires a prospective, randomized, placebo-controlled trial.

 Iron and Fever

Warm-blooded animals have an elaborate physiological control system to maintain a constant body temperature. In man, this temperature is about 37°C. Any significant deviation from this temperature puts stress on the body and makes it difficult to maintain metabolic processes at their normal rates. Why then, during sickness, should the temperature rise? It would seem that development of fever would cause things to go from bad to worse, and make it more difficult for the body to recuperate. Fe...

 Fever Reducing Medicines Increase the Spread of Infection

To put our lower bound for fp into perspective, consider that approximately 41 400 (95% CI: 27 100–55 700) deaths per year are attributed to seasonal influenza epidemics in the United States [43] (and an order of magnitude more worldwide [44]). Taken at face value, our results indicate, for example, that if Embedded Image then at least 700 deaths per year (95% CI: 30–2100) (and many more serious illnesses) could be prevented in the US alone by avoiding antipyretic medication for the treat...