1945 Warning of Bacterial Antibiotic Resistance

But I would like to sound one note of warning. Penicillin is to all intents and purposes non-poisonous so there is no need to worry about giving an overdose and poisoning the patient. There may be a danger, though, in underdosage. It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body. The time may come when penicillin can be bought by anyone in the...

 Governments Can't Control Science

Faced with the admitted difficulty of managing the creative process, we are doubling our efforts to do so. Is this because science has failed to deliver, having given us nothing more than nuclear power, penicillin, space travel, genetic engineering, transistors, and superconductors? Or is it because governments everywhere regard as a reproach activities they cannot advantageously control? They felt that way about the marketplace for goods, but trillions of wasted dollars later, they have come...

 Gertrude B. Elion's Tragedy

I had fallen in love with a young man..., and we were planning to get married. And then he died of subacute bacterial endocarditis... Two years later with the advent of penicillin, he would have been saved. It reinforced in my mind the importance of scientific discovery...

 We Should have a Saints Day for Penicillin

... we ought to have saints' days to commemorate the great discoveries which have been made for all mankind, and perhaps for all time—or for whatever time may be left to us. Nature ... is a prodigal of pain. I should like to find a day when we can take a holiday, a day of jubilation when we can fête good Saint Anaesthesia and chaste and pure Saint Antiseptic. ... I should be bound to celebrate, among others, Saint Penicillin...

 Penicilin Resistant Staphylococcus

Another prime example of selection is resistance to penicillin. When it was introduced in the early 1940s, penicillin was a miracle drug, especially effective at curing infections caused by the bacteria Staphylococcus aureus (“staph”). In 1941, the drug could wipe out every strain of staph in the world. Now, seventy years later, more than 95 percent of staph strains are resistant to penicillin. What happened was that mutations occurred in individual bacteria that gave them the ability to ...

 Science VS Belief

Science seeks the truth. And it does not discriminate. For better or worse it finds things out. Science is humble. It knows what it knows and it knows what it doesn’t know. It bases its conclusions and beliefs on hard evidence -­- evidence that is constantly updated and upgraded. It doesn’t get offended when new facts come along. It embraces the body of knowledge. It doesn’t hold on to medieval practices because they are tradition. If it did, you wouldn’t get a shot of penicillin, yo...