"Scandals" - Animals Evolved from Cancer Cells

Panchin knows the idea of cancer-derived animals sounds far-fetched — so much so that, in the paper, he and his co-authors refer to them as Scandals (an acronym for “speciated by cancer development animals”). [...] According to Panchin’s three-step scenario, a Scandal would start off as a cancer, but not just any cancer. It would have to be transmissible, so that it wouldn’t die when its host did. Then the cancer would have to spread to other species, and then independently evolve...

 Hawking Considers Computer Viruses Life

A living being like you or me usually has two elements: a set of instructions that tell the system how to keep going and how to reproduce itself, and a mechanism to carry out the instructions. In biology, these two parts are called genes and metabolism. But it is worth emphasising that there need be nothing biological about them. For example, a computer virus is a program that will make copies of itself in the memory of a computer, and will transfer itself to other computers. Thus it fits the...

 The Myth of the Solitary Villain

The more sophisticated and powerful a technology, the more people are needed to weaponize it. And the more people needed to weaponize it, the more societal controls work to defuse, or soften, or prevent harm from happening. I add one additional thought. Even if you had a budget to hire a team of scientists whose job it was to develop a species-extinguishing bio weapon, or to take down the internet to zero, you probably still couldn’t do it. That’s because hundreds of thousands of man-year...

 Neurons Use Viruses to Share Information and Learn

When genes are activated, the instructions encoded within their DNA are first transcribed into a related molecule called RNA. Shepherd’s colleague Elissa Pastuzyn showed that the Arc shells can enclose RNA and move it from one neuron to another. And that’s basically what retroviruses do—they use protein shells to protect their own RNA as it moves between cells in a host. So our neurons use a repurposed viral gene to transmit genetic information between each other in an oddly virus-like...

 Nicotinamide riboside (NR) Increases NADP

In the first controlled clinical trial of nicotinamide riboside (NR), a newly discovered form of Vitamin B3, researchers have shown that the compound is safe for humans and increases levels of a cell metabolite that is critical for cellular energy production and protection against stress and DNA damage. Studies in mice have shown that boosting the levels of this cell metabolite—known as NAD —can produce multiple health benefits, including resistance to weight gain, improved control of bl...

 Falacy of Seeking Too Much Purpose in Evolutionary Adapta...

Darwin’s concept of evolution is centered on natural selection, or survival of the fittest [1]. Although Darwin did realize that organisms possess structures and even entire organs that might not have an extant function, as is the case of rudiments [2], on the whole, selectionist thinking has heavily dominated the biological literature ever since. In its extreme but not uncommon form, the selectionist, or adaptationist, paradigm perceives every trait as an adaptation. Under this view of bio...