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Memes with the Watson keyword “central problem”

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Error Catastrophe

The central problem for any theory of the origin of replication is the fact that a replicative apparatus has to function almost perfectly if it is to function at all. If it does not function perfectly, it will give rise to errors in replicating itself, and the errors will accumulate from generation to generation. The…

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Chance Favors, but Ambition is Crucial

The major credit I think Jim and I deserve ... is for selecting the right problem and sticking to it. It's true that by blundering about we stumbled on gold, but the fact remains that we were looking for gold. Both of us had decided, quite independently of each other, that the central problem in molecular biology was…

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