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Of the 20,000 to 30,000 genes now thought to be in the human genome, most cells express only a very small part - which makes sense, a liver cell has little need for the DNA code that makes neurons. But as almost all cells carry around a full copy ('distribution') of the genome, a system is needed to #ifdef out stuff…
Each of us is ordinary, yet one of a kind. Each of us is standard issue, conceived by the union of two germ cells, nurtured in a womb, and equipped with a developmental program that guides our further maturation and eventual decline. Each of us is also unique, the possessor of a particular selection of gene variants…
Ideas are what power our economy. It’s what sets us apart. It’s what America has been all about. We have been a nation of dreamers and risk-takers; people who see what nobody else sees sooner than anybody else sees it. We do innovation better than anybody else — and that makes our economy stronger. When we invest in…
The genome is not a blueprint for constructing a body; it is a recipe for baking a body. As the hox story illustrates, DNA promoters express themselves in the fourth dimension; their timing is all. A chimp has a different head from a human being not because it has a different blueprint for the head, but because it…