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In the first controlled clinical trial of nicotinamide riboside (NR), a newly discovered form of Vitamin B3, researchers have shown that the compound is safe for humans and increases levels of a cell metabolite that is critical for cellular energy production and protection against stress and DNA damage. Studies in…
The awesome power that genetic engineering will one day place in our hands was foreshadowed recently by some experimenters at the University of Basel in Switzerland. Walter Gehring and his students were studying the effects of the eyeless gene in fruit flies. The gene is called eyeless because its absence causes flies…
This reversibility and this polyvalency endow analogy with a universal field of application. Through it, all the figures in the whole universe can be drawn together. There does exist, however, in this space, furrowed in every direction, one particularly privileged point: it is saturated with analogies (all analogies…
Endless eXtension - Extropists seek perpetual growth and progress in all aspects of human endeavor. We are, as a species and as a culture, never finished or in any essential way complete. Instead, we continually pursue knowledge, we constantly experiment, we forever continue to develop techniques that improve our…
Control of fire and the capacity for cooking led to major anatomical and residential changes for early humans, starting more than a million years ago. However, little is known about what transpired when the day was extended by firelight. Data from the Ju/’hoan hunter-gatherers of southern Africa show major differences…
All tools are externalizations of originally integral functions. But in developing each tool man also extends the limits of its usefulness, since he can make bigger cups hold liquids too hot or chemically destructive for his hands. Tools do not introduce new principles but they greatly extend the range of conditions…
Some physiologists will have it that the stomach is a mill; others, that it is a fermenting vat; others, again that it is a stew-pan; but in my view of the matter, it is neither a mill, a fermenting vat nor a stew-pan, but a stomach gentlemen, a stomach.
Muscles are in a most intimate and peculiar sense the organs of the will. They have built all the roads, cities and machines in the world, written all the books, spoken all the words, and, in fact done everything that man has accomplished with matter. Character might be a sense defined as a plexus of motor habits.
The occurrence of an internal skeleton, in definite relations to the other organ systems, and the articulation of the body into homologous segments, are points in the general organization of Vertebrates to which especial weight must be given. This metameric structure is more or less definitely expressed in most of the…
Nature may be as selfishly studied as trade. Astronomy to the selfish becomes astrology; psychology, mesmerism (with intent to show where aour spoons are gone); and anatomy and physiology become phrenology and palmistry.
The recent trend of putting young babies to sleep on their backs also appears to be having an effect on their motor skill acquisition. This posture, which has proven advantageous in reducing the number of SIDS fatalities, does not permit babies to exercise their arm and neck muscles as much as and see the world. In…
Staring at that skull, I was struck by the fact that this ancient child was somebody's baby long ago. Perhaps she was sick, or maybe he e was accident-prone, or perhaps this baby was some predator's dinner. Standing there, I could picture him or her long ago, I, smiling, laughing, and reaching out to grab a mother's…
What a piece of work is the mammalian skeleton. I don't mean it is beautiful in itself, although I think it is. I mean the fact that we can talk about 'the' mammalian skeleton at all: the fact that such a complicatedly interlocking thing is so gloriously different across the mammals, in all its parts, while…