Periodicals>Journal Article: Stein, Medland, Vasquez (15 April 2012), Identification of common variants associated with human hippocampal and intracranial volumes, Nature Genetics, Retrieved on 2012-04-16Source Material [www.nature.com]
Folksonomies: genes genetics Memes
16 APR 2012
Genes Associated with Brain Volume
Identifying genetic variants influencing human brain structures may reveal new biological mechanisms underlying cognition and neuropsychiatric illness. The volume of the hippocampus is a biomarker of incipient Alzheimer's disease1, 2and is reduced in schizophrenia3, major depression4 and mesial temporal lobe epilepsy5. Whereas many brain imaging phenotypes are highly heritable6, 7, identifying and replicating genetic influences has been difficult, as small effects and the high costs of mag...SNPs: rs7294919(T;T), rs10784502(C;T), and rs10494373(A;A) tied to brain volume.