Claude Shannon's "Entropy House"

Built in 1858, the house was constructed for Ellen Dwight, a great-granddaughter of a genius tinkerer of an earlier era, Thomas Jefferson. Originally seated on twelve acres, its design was inspired by Monticello. Encircled by “a three-sided verandah with segmental openings and chamfered posts,” the house was a stately three stories at the crest of a “broad expanse of lawn reaching down to the wooded shore of Upper Mystic Lake.” Toward the end of Shannon’s life, it was added to the N...

 The Placenta and Toxicity

“During most of pregnancy, the placenta separating mother and fetus is only one cell thick,” Koren tells me. “But it has an array of mechanisms to help it do its job of protecting the fetus.” These subcellular tools, he explains, include tiny pumps that expel toxins before they can do any damage, immune agents that guard the placenta’s perimeter, and placental enzymes that chemically break down intruding molecules. This armamentarium does an impressive job of blocking bacteria from...