Invasive Blood-Seeking Fetuses in Mammals

In most mammals, the mother’s blood supply remains safely isolated from the foetus. It passes its nutrients to the foetus through a filter, which the mother controls. The mother is a despot: she provides only what she chooses, which makes her largely invulnerable to paternal manipulation during pregnancy.

In primates and mice, it’s a different story. Cells from the invading placenta digest their way through the endometrial surface, puncturing the mother’s arteries, swarming inside and remodelling them to suit the foetus. Outside of pregnancy, these arteries are tiny, twisty things spiralling through depths of the uterine wall. The invading placental cells paralyse the vessels so they cannot contract, then pump them full of growth hormones, widening them tenfold to capture more maternal blood. These foetal cells are so invasive that colonies of them often persist in the mother for the rest of her life, having migrated to her liver, brain and other organs. There’s something they rarely tell you about motherhood: it turns women into genetic chimeras.

Perhaps this enormous blood supply explains why primates have brains five to ten times larger than the average mammal. Metabolically speaking, brains are extremely expensive organs, and most of their growth occurs before birth. How else is the fetus to fund such extravagance?

Notes:

Folksonomies: evolution pregnancy

Taxonomies:
/family and parenting/motherhood/pregnancy (0.594364)
/health and fitness/disease (0.293779)
/technology and computing/hardware/computer peripherals (0.262305)

Keywords:
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Concepts:
Fetus (0.948105): dbpedia | freebase | opencyc
Embryo (0.883093): dbpedia | freebase | opencyc
Pregnancy (0.847846): dbpedia | freebase | opencyc
Placenta (0.758417): dbpedia | freebase | opencyc
Mammal (0.716356): dbpedia | freebase | opencyc
Uterus (0.656098): dbpedia | freebase | opencyc
Blood (0.629675): dbpedia | freebase | opencyc
Heart (0.535043): dbpedia | freebase | opencyc

 War in the womb
Electronic/World Wide Web>Internet Article:  Sadedin, Suzanne (8/4/2014), War in the womb, Retrieved on 2014-08-08
  • Source Material [aeon.co]
  • Folksonomies: evolution pregnancy